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Proposed roles include maintenance of tightjunction barriers, signaling and junction remodeling.
2
PKC-ζ inhibition also attenuated AGE-induced decrease of tightjunction proteins in HRMECs.
3
Results showed reversible recovery on the expression of tightjunction markers.
4
Proteins responsible for tightjunction integrity are upregulated in hypertonic states.
5
The tightjunction of epithelial cells excludes macromolecules but allows permeation of ions.
1
Microvillis and zonulaoccludens were observed on the surface of the differentiated cells under an electron microscope.
2
Most gap junctions between neurons in mammalian retina contain abundant connexin36, often in association with the scaffolding protein zonulaoccludens-1.
3
The expression and membrane localization of the tight junction proteins zonulaoccludens-1 and occludin were decreased in alveolar epithelial cells from HIV-1 transgenic rats.
1
Sequestration of CAR in tightjunctions may limit virus infection across epithelial surfaces.
2
They create tightjunctions with mouse hepatocytes, with no evidence of cell fusion.
3
This isoform of TOCA-1 recruits the actin nucleation-promoting factor N-WASP to tightjunctions.
4
JAM-A localizes to tightjunctions and contributes to paracellular permeability in polarized epithelia.
5
Adherens junctions are calcium dependent; recent evidence suggests that calcium also affects tightjunctions.